Opportunity Information: Apply for RFA HD 18 034

The funding opportunity titled "Advancing the Science of Multipurpose Technology for the Prevention of HIV and Unintended Pregnancy (R41/R42)" was an NIH small business grant solicitation intended to support research and development of multipurpose prevention technologies (often referred to as MPTs). In practical terms, these are products or approaches designed to address more than one sexual and reproductive health need at the same time, with this particular call focusing on preventing HIV and preventing unintended pregnancy. The mechanism listed, R41/R42, indicates the NIH Small Business Innovation Research (SBIR) phased structure, where R41 generally aligns with early-stage feasibility work (Phase I) and R42 aligns with more advanced development activities (Phase II), typically moving an idea from proof-of-concept toward a more mature prototype or validated technology.

Administratively, this specific announcement (Funding Opportunity Number RFA HD 18 034) was categorized as a discretionary grant under the Health, Income Security and Social Services activity category, and it was associated with CFDA number 93.865. The sponsoring agency was the National Institutes of Health. The eligible applicant type was small businesses, reflecting that the opportunity was structured for U.S. small business concerns rather than universities or large nonprofits as primary applicants. While the listing references an original closing date of 2017-11-07 and a creation date of 2017-11-06, the central detail that governs its status is that the announcement was released early in error, was closed, and was explicitly slated to be reissued later under a different funding opportunity announcement number. In other words, even though the opportunity appeared briefly with an application deadline, NIH closed it and indicated that applicants should watch for a replacement solicitation rather than attempt to apply under this one.

On eligibility and foreign involvement, the notice is clear that non-domestic (non-U.S.) entities (foreign institutions) were not eligible to apply as applicants, and non-domestic components of U.S. organizations were also not eligible to apply. That said, the notice leaves room for "foreign components" as defined by the NIH Grants Policy Statement to be allowed. This distinction matters because it means the applicant organization had to be an eligible U.S. small business, but certain project elements might have been permitted to occur outside the United States if they met NIH policy definitions and were appropriately justified and approved. The key takeaway is that the applicant itself could not be a foreign institution, and a U.S. organization could not apply through an ineligible non-U.S. component, but limited foreign collaboration or performance sites might still have been possible under NIH rules.

Several standard fields in the source data, such as award ceiling and expected awards, are left blank, suggesting that the public-facing record did not specify a maximum award amount or the anticipated number of awards at the time of posting (or that these details were not captured in the summary record). Overall, the opportunity represents an NIH SBIR initiative aimed at accelerating innovation in combined HIV prevention and contraception technologies, but this particular posting should be treated as inactive because it was issued prematurely, formally closed, and intended to be replaced with a new announcement number at a later date.

  • The National Institutes of Health in the health, income security and social services sector is offering a public funding opportunity titled "Advancing the Science of Multipurpose Technology for the Prevention of HIV and Unintended Pregnancy (R41/R42)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.865.
  • This funding opportunity was created on 2017-11-06.
  • Applicants must submit their applications by 2017-11-07. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Small businesses.
Apply for RFA HD 18 034

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FAQs: Advancing the Science of Multipurpose Technology for the Prevention of HIV and Unintended Pregnancy (R41/R42)

What is the title of this funding opportunity?

The funding opportunity is titled "Advancing the Science of Multipurpose Technology for the Prevention of HIV and Unintended Pregnancy (R41/R42)."

What is the main purpose of this grant solicitation?

The purpose is to support research and development of multipurpose prevention technologies (MPTs) designed to address more than one sexual and reproductive health need at the same time, with this call specifically focused on preventing HIV and preventing unintended pregnancy.

What are multipurpose prevention technologies (MPTs) in the context of this opportunity?

In this context, MPTs are products or approaches intended to provide combined protection, specifically targeting both HIV prevention and prevention of unintended pregnancy within a single technology or strategy.

Which agency sponsored this opportunity?

The sponsoring agency was the National Institutes of Health (NIH).

What funding mechanism does R41/R42 refer to?

R41/R42 refers to the NIH Small Business Innovation Research (SBIR) phased structure. R41 generally aligns with Phase I (early-stage feasibility work), and R42 generally aligns with Phase II (more advanced development activities), typically moving a project from proof-of-concept toward a more mature prototype or validated technology.

Is this opportunity part of the NIH SBIR program?

Yes. The R41/R42 mechanism indicates it was an NIH SBIR solicitation intended for eligible U.S. small business concerns.

Who was eligible to apply?

The eligible applicant type listed was small businesses. The opportunity was structured for U.S. small business concerns rather than universities or large nonprofits as primary applicants.

Are foreign (non-U.S.) institutions eligible to apply as applicants?

No. Non-domestic (non-U.S.) entities (foreign institutions) were not eligible to apply as applicants under this notice.

Can a U.S. organization apply through a non-U.S. component?

No. Non-domestic components of U.S. organizations were also not eligible to apply under this solicitation.

Does the notice allow any foreign involvement at all?

Yes, potentially. While foreign institutions could not be the applicant (and non-U.S. components of U.S. organizations were not eligible), the notice indicates that "foreign components" (as defined by the NIH Grants Policy Statement) could be allowed. This suggests the applicant had to be an eligible U.S. small business, but certain project elements might have been permitted to occur outside the United States if they met NIH policy definitions and were appropriately justified and approved.

What is the Funding Opportunity Number (FOA number) for this posting?

The Funding Opportunity Number listed was RFA HD 18 034.

What is the CFDA number associated with this opportunity?

The CFDA number associated with this opportunity was 93.865.

How was this opportunity categorized administratively?

It was categorized as a discretionary grant under the Health, Income Security and Social Services activity category.

What was the original closing date shown for this opportunity?

The listing references an original closing date of 2017-11-07.

What was the creation date shown in the listing?

The listing references a creation date of 2017-11-06.

Is this funding opportunity currently active and accepting applications?

No. The announcement was released early in error, was closed, and was explicitly slated to be reissued later under a different funding opportunity announcement number.

Should applicants apply under this FOA number (RFA HD 18 034)?

No. Based on the notice, applicants were expected to watch for a replacement solicitation (a reissued announcement under a different FOA number) rather than attempt to apply under this one.

Will this opportunity be reissued?

Yes. The notice states it was closed and intended to be reissued later under a different funding opportunity announcement number.

Does the public summary specify an award ceiling (maximum award amount)?

No. Standard fields such as award ceiling were left blank in the source data, indicating the public-facing record did not specify a maximum award amount (or that the detail was not captured in the summary record).

Does the public summary specify the expected number of awards?

No. The expected number of awards field was also left blank, suggesting the anticipated number of awards was not specified in the posted summary (or was not captured there).

What stage of development was NIH trying to support with this solicitation?

The use of the SBIR phased R41/R42 structure indicates NIH intended to support both early feasibility work (Phase I) and more advanced development (Phase II), moving concepts from proof-of-concept toward more mature prototypes or validated technologies.

What is the key status takeaway for someone evaluating this posting?

The key takeaway is that this specific posting should be treated as inactive: it was issued prematurely, formally closed, and intended to be replaced by a new announcement number.

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