Opportunity Information: Apply for IR ORI 25 003
The Ensuring Research Integrity - Program Development and Evaluation Program (PDE) is a discretionary grant opportunity from the Office of Research Integrity (ORI) within the Office of the Assistant Secretary for Health. Its focus is practical and outcomes-driven: supporting the development, implementation, and evaluation of new approaches that strengthen research integrity and help prevent research misconduct. ORI is looking for projects that translate evidence into action, including interventions informed by empirical findings (such as prior ORI-funded research) and tools that can help identify individuals, labs, or environments that may be at higher risk for misconduct or other harmful research practices.
The opportunity is designed around three main project directions, and applicants can propose work that covers one, two, or all three. The first area is educational resource development. This can include creating new online training modules that go beyond static content by using interactive scenarios to teach research integrity principles in realistic situations. It also includes designing engaging in-person or classroom-based programs that reinforce responsible conduct of research, reduce the likelihood of misconduct, and encourage appropriate reporting when misconduct is suspected. A key expectation is evaluation: projects should assess whether these training and educational resources actually work, not just whether they were produced.
The second area is the creation of risk assessment tools intended for real-world administrative use. ORI is interested in tools that principal investigators, department chairs, research administrators, or similar leaders can use to assess risk for individuals, laboratories, or research programs engaging in misconduct or detrimental research practices. This category also covers tools that assess institutional research culture, norms, or operational practices that may contribute to misconduct risk. As with the education track, development is not enough on its own; applicants are expected to design, test, and evaluate the effectiveness and usefulness of the resulting assessment tool(s).
The third area is implementation and testing of intervention programs that can be piloted in research settings. Examples highlighted include interventions to improve lab data management and record-keeping, paired with pre- and post-assessments to measure changes related to research integrity. Another example is mentorship and leadership training programs intended to build an ethical, responsible research culture from the top down and within day-to-day supervision. Here again, evaluation is central: ORI is looking for evidence that an intervention measurably improves practices, culture, or integrity-related outcomes.
From an intellectual property and data rights standpoint, recipients generally retain copyright for materials they develop under the award. However, consistent with federal grant regulations (45 C.F.R. 75.322), HHS keeps a royalty-free, nonexclusive, irrevocable right to reproduce, publish, or otherwise use those materials for federal purposes, and to authorize others to do the same. Similarly, the federal government retains broad rights to obtain and use data produced under the award for federal purposes and to authorize others to use those data. In practical terms, awardees can still own what they create, but they should plan for government reuse and sharing for public benefit.
The anticipated project structure is up to 24 months total, organized into two 12-month budget periods. After the first year, recipients must submit a non-competing continuation (NCC) application to receive the second year of support. Continuation depends on funds availability, satisfactory progress, responsible financial stewardship, and alignment with government interests. Funding for later periods is generally expected to match the initial amount, though it can be adjusted if there are unused funds carried over from the prior period.
Funding details in the posting indicate an award ceiling of $75,000, with an expectation of making about two awards. The application deadline listed is April 10, 2025. The program is listed under CFDA 93.085, and the activity category aligns with education and research and development in science and technology-related areas.
Eligibility is broad and includes many types of U.S. and tribal government entities, public and private institutions of higher education, nonprofits (both 501(c)(3) and non-501(c)(3)), for-profit organizations (including small businesses), independent school districts, special district governments, and public housing authorities/Indian housing authorities. ORI also indicates that universities, hospitals, laboratories, other public or private institutions, and individuals may apply. Faith-based organizations, community-based organizations, and American Indian/Alaska Native/Native American organizations are explicitly included. Foreign organizations and foreign components of domestic organizations may also be eligible when the project provides a domestic benefit, such as improving research integrity among Public Health Service (PHS)-funded institutions in the U.S. and abroad.
Overall, this grant is aimed at producing usable integrity infrastructure: training that changes behavior, tools that help leaders detect and reduce risk, and interventions that measurably improve research practices and culture, all within a relatively short, evaluation-heavy two-year window and with an expectation that outputs and data can be leveraged for broader federal and public purposes.Apply for IR ORI 25 003
- The Office of the Assistant Secretary for Health in the education, science and technology and other research and development sector is offering a public funding opportunity titled "Ensuring Research Integrity - Program Development and Evaluation Program (PDE)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.085.
- This funding opportunity was created on 2024-07-31.
- Applicants must submit their applications by 2025-04-10. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $75,000.00 in funding.
- The number of recipients for this funding is limited to 2 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses.
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Ensuring Research Integrity (ERI) - Program Development and Evaluation (PDE) FAQs
What is the Ensuring Research Integrity - Program Development and Evaluation (PDE) grant?
The Ensuring Research Integrity - Program Development and Evaluation Program (PDE) is a discretionary grant opportunity from the Office of Research Integrity (ORI) within the Office of the Assistant Secretary for Health. It supports practical, outcomes-driven projects that develop, implement, and evaluate new approaches to strengthen research integrity and help prevent research misconduct.
What is ORI looking for in funded projects?
ORI is looking for projects that translate evidence into action. This includes interventions informed by empirical findings (including prior ORI-funded research) and tools that can help identify individuals, labs, or environments that may be at higher risk for misconduct or other harmful research practices. Across all project types, evaluation is a central expectation.
What are the main project directions under this opportunity?
The opportunity is organized around three project directions. Applicants may propose work in one, two, or all three areas:
- Educational resource development
- Creation of risk assessment tools for administrative use
- Implementation and testing of intervention programs in research settings
What counts as "educational resource development" for this program?
Educational resource development can include creating new online training modules that go beyond static content by using interactive scenarios to teach research integrity principles in realistic situations. It can also include designing engaging in-person or classroom-based programs that reinforce responsible conduct of research, reduce the likelihood of misconduct, and encourage appropriate reporting when misconduct is suspected.
Is producing training content enough, or does ORI require evaluation?
Evaluation is a key expectation. Projects should assess whether the training and educational resources are effective, not merely whether they were created or delivered.
What kinds of risk assessment tools does ORI want to fund?
ORI is interested in risk assessment tools intended for real-world administrative use. These are tools that principal investigators, department chairs, research administrators, or similar leaders can use to assess risk for individuals, laboratories, or research programs engaging in misconduct or detrimental research practices.
Can risk assessment tools focus on institutional culture and practices?
Yes. This category also includes tools that assess institutional research culture, norms, or operational practices that may contribute to misconduct risk.
Do risk assessment tools have to be tested and evaluated?
Yes. ORI expects applicants not only to develop tools, but also to design, test, and evaluate the effectiveness and usefulness of the resulting assessment tool(s).
What are examples of intervention programs that could be supported?
Examples highlighted include interventions to improve lab data management and record-keeping, paired with pre- and post-assessments to measure changes related to research integrity. Another example is mentorship and leadership training programs intended to build an ethical, responsible research culture through supervision and leadership practices.
How important is evaluation for intervention projects?
Evaluation is central. ORI is looking for evidence that an intervention measurably improves practices, culture, or integrity-related outcomes.
How long is the project period for this grant?
The anticipated project structure is up to 24 months total, organized into two 12-month budget periods.
What is a non-competing continuation (NCC) application, and when is it required?
After the first 12-month budget period, recipients must submit a non-competing continuation (NCC) application to receive the second year of support.
What determines whether the second year of funding is awarded?
Continuation depends on funds availability, satisfactory progress, responsible financial stewardship, and alignment with government interests.
Will the second-year funding amount be the same as the first year?
Funding for later periods is generally expected to match the initial amount, though it can be adjusted if there are unused funds carried over from the prior period.
What is the award ceiling for this opportunity?
The posting indicates an award ceiling of $75,000.
How many awards does ORI expect to make?
The opportunity indicates an expectation of making about two awards.
What is the application deadline?
The listed application deadline is April 10, 2025.
What is the CFDA number for this program?
The program is listed under CFDA 93.085.
What types of organizations are eligible to apply?
Eligibility is broad and includes many types of entities, including:
- U.S. and tribal government entities
- Public and private institutions of higher education
- Nonprofits (both 501(c)(3) and non-501(c)(3))
- For-profit organizations (including small businesses)
- Independent school districts
- Special district governments
- Public housing authorities and Indian housing authorities
- Faith-based organizations
- Community-based organizations
- American Indian/Alaska Native/Native American organizations
Can individuals apply for this grant?
Yes. ORI indicates that individuals may apply, along with universities, hospitals, laboratories, and other public or private institutions.
Are foreign organizations or foreign components eligible?
Foreign organizations and foreign components of domestic organizations may also be eligible when the project provides a domestic benefit, such as improving research integrity among Public Health Service (PHS)-funded institutions in the U.S. and abroad.
Who is expected to use the tools or resources developed under this program?
Depending on the project direction, intended users can include research trainees and staff (for education resources), and research leadership and oversight roles such as principal investigators, department chairs, and research administrators (for risk assessment and administrative tools).
What are the intellectual property (IP) expectations for materials created with grant funds?
Recipients generally retain copyright for materials they develop under the award. However, consistent with federal grant regulations (45 C.F.R. 75.322), HHS retains a royalty-free, nonexclusive, irrevocable right to reproduce, publish, or otherwise use those materials for federal purposes, and to authorize others to do the same.
What rights does the federal government have to data produced under the award?
The federal government retains broad rights to obtain and use data produced under the award for federal purposes and to authorize others to use those data.
What does government reuse and sharing mean in practical terms for awardees?
In practical terms, awardees can still own what they create, but they should plan for government reuse and sharing of materials and data for federal purposes and broader public benefit.
What is the overall goal of this grant opportunity?
The overall goal is to produce usable research integrity infrastructure within a relatively short, evaluation-heavy two-year window. This includes training that changes behavior, tools that help leaders detect and reduce risk, and interventions that measurably improve research practices and culture, with outputs and data that can be leveraged for broader federal and public purposes.
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